Jornal Vascular Brasileiro
https://jvascbras.org/article/doi/10.1590/1677-5449.008416
Jornal Vascular Brasileiro
Therapeutic Challenge

Cateterismo de artéria mesentérica para tratamento de trombose de veia porta

Catheterization of the mesenteric artery to treat portal vein thrombosis

Guilherme Benjamin Brandão Pitta, Deise Azevedo Pereira, Milena de Fátima Queiroz Oliveira, Eduardo Abadie Guedes, Joaquim Araújo Sampaio

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Resumo

A trombose de veia porta é uma causa rara de abdome agudo vascular e está diretamente relacionada a trombofilias hereditárias ou adquiridas. O caso de um paciente de 60 anos, sexo masculino, com quadro clínico de isquemia mesentérica confirmada por exame de imagem é apresentado. Foi submetido a enterectomia e enteroanastomose e, após esplenoportografia que detectou trombose de veia porta, indicou-se tratamento medicamentoso com infusão contínua de ativador tecidual do plasminogênio recombinante (Alteplase) através de cateterismo seletivo da artéria mesentérica superior. Trata-se de um tratamento inovador. Obteve-se sucesso na recanalização do sistema porta. O paciente evoluiu com quadro de sepse abdominal, necessitando de assistência em terapia intensiva por 25 dias. Evoluiu bem e recebeu alta hospitalar com o uso de anticoagulante. O artigo apresenta uma breve revisão de literatura e discussão do caso clínico.

Palavras-chave

veia porta; trombose; trombofilia; isquemia mesentérica; abdome agudo

Abstract

Portal vein thrombosis is a rare vascular cause of acute abdomen and it is directly related to hereditary or acquired thrombophilias. This article presents the case of a 60-year-old male patient, with clinical signs of mesenteric ischemia that was confirmed by imaging examination. He underwent enterectomy and enteroanastomosis and, after detection of portal vein thrombosis by splenoportography, he was prescribed drug-based treatment with continuous infusion of recombinant tissue plasminogen activator (Alteplase) via selective catheterization of the superior mesenteric artery. This is a treatment innovation. The portal system was successfully recanalized. However, the patient developed abdominal sepsis and required intensive care for 25 days. His clinical status improved and he was discharged with a prescription for oral anticoagulant. This article presents a brief review of the literature and a discussion of portal vein thrombosis.

Keywords

portal vein; thrombosis; thrombophilia; mesenteric ischemia; acute abdomen.

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