Improvement of semen parameters after coil embolization of varicoceles: a systematic review
Melhora dos parâmetros seminais após embolização com molas de varicocele: uma revisão sistemática
Sergio Quilici Belczak; Vanessa Stefaniak; Leonardo Garcia Góes; Felipe Coelho Neto; Walter Jr. Boim de Araújo; Nathalia Almeida Cardoso da Silva
Abstract
Keywords
Resumo
Resumo: Trata-se de uma revisão sistemática conduzida de acordo com o PRISMA 2009 (Principais Itens para Relatar Revisões Sistemáticas e Metanálises) que incluiu estudos em que a melhora dos parâmetros seminais tenha sido um dos desfechos. Esta revisão foi realizada com o objetivo de avaliar as evidências sobre o papel da embolização com uso apenas de molas na melhora de parâmetros seminais em homens com varicocele, uma vez que a embolização apenas com molas é o método com melhor custo-benefício para o reparo de varicoceles. A qualidade dos estudos foi analisada com o índice MINORS. Em seis estudos clínicos retrospectivos e em outros dois prospectivos observacionais ou comparativos, a concentração seminal melhorou significativamente em todos os cinco estudos que avaliaram esse parâmetro. A motilidade seminal melhorou significativamente em sete estudos. Não foi possível analisar o impacto da embolização com molas na densidade seminal.
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References
1 Wagner L, Tostain J. Varicocèle et infertilité masculine: recommandations comité andrologie - AFU 2006. Prog Urol. 2007;17(1):12-7.
2 World Health Organization – WHO.The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics. Fertil Steril. 1992;57(6):1289-93.
3 Tulloch WS. Varicocele in subfertility; results of treatment. BMJ. 1955;2(4935):356-8.
4 Baazeem A, Belzile E, Ciampi A, et al. Varicocele and male factor infertility treatment: a new meta-analysis and review of the role of varicocele repair. Eur Urol. 2011;60(4):796-808.
5 Evers JL, Collins JA, Vandekerckhove P. Surgery or embolisation for varicocele in subfertile men. Cochrane Database Syst Rev. 2001;(1):CD000479.
6 Evers JL, Collins JA, Clarke J. Surgery or embolisation for varicocele in subfertile men. Cochrane Database Syst Rev. 2004;(3):CD000479.
7 Evers JHLH, Collins J, Clarke J. Surgery or embolization of varicoceles in subfertile men. Cochrane Database Syst Rev. 2009;(1):CD000479.
8 Marmar JL, Agarwal A, Prabakaran S, et al. Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis. Fertil Steril. 2007;88(3):639-48.
9 Weidner W, Diemer T. Re: Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis. Eur Urol. 2008;54(2):465-6.
10 Lima SS, Castro MP, Costa OF. A new method for the treatment of varicocele. Andrologia. 1978;10(2):103-6.
11 Ali A, Wirth S, Treitl KM, Treitl M. Treatment of male varicoceles by transcatheter polidocanol foam sclerotherapy: evaluation of clinical success, complications, and patients’ satisfaction with regard to alternative techniques. Eur Radiol. 2015;25(10):2889-97.
12 Bechara CF, Weakley SM, Kougias P, et al. Percutaneous treatment of varicocele with microcoil embolization: comparison of treatment outcome with laparoscopic varicocelectomy. Vascular. 2009;17(Suppl. 3):S129-36.
13 Gandini R, Konda D, Reale CA, et al. Male varicocele: transcatheter foam sclerotherapy with sodium tetradecyl sulfate--outcome in 244 patients. Radiology. 2008;246(2):612-8.
14 Makris GC, Efthymiou E, Little M, et al. Safety and effectiveness of the different types of embolic materials for the treatment of testicular varicoceles: a systematic review. Br J Radiol. 2018;91(1088):20170445.
15 Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J. Methodological index for non-randomized studies (MINORS): development and validation of a new instrument. ANZ J Surg. 2003;73(9):712-6.
16 Prasivoravong J, Marcelli F, Lemaitre L, et al. Beneficial effects of varicocele embolization on semen parameters. Basic Clin Androl. 2014;24(1):9.
17 Cantoro U, Polito M, Muzzonigro G. Reassessing the role of subclinical varicocele in infertile men with impaired semen quality: a prospective study. Urology. 2015;85(4):826-30.
18 Ferguson JM, Gillespie IN, Chalmers N, Elton RA, Hargreave TB. Percutaneous varicocele embolization in the treatment of infertility. Br J Radiol. 1995;68(811):700-3.
19 Punekar SV, Prem AR, Ridhorkar HK, Deshmukh HL, Kelkar AR. Post-surgical recurrent varicocele: efficacy of internal spermatic venography and steel-coil embolization. Br J Urol. 1996;77(1):124-8.
20 Shlansky-Goldberg RD, VanArsdalen KN, Rutter CM, et al. Percutaneous varicocele embolization versus surgical ligation for the treatment of infertility: changes in seminal parameters and pregnancy outcomes. J Vasc Interv Radiol. 1997;8(5):759-67.
21 Tanahatoe SJ, Maas WM, Hompes PG, Lambalk CB. Influence of varicocele embolization on the choice of infertility treatment. Fertil Steril. 2004;81(6):1679-83.
22 Nabi G, Asterlings S, Greene DR, Marsh RL. Percutaneous embolization of varicoceles: outcomes and correlation of semen improvement with pregnancy. Urology. 2004;63(2):359-63.
23 Binhazzaa M, Bounasr E, Perez G, et al. Comparaison de la cure de le varicocèle par ligature microchirurgicale subinguinale vs embolisation percutanée chez l’homme infertile. Prog Urol. 2016;26(16):1178-84.
24 Schlesinger MH, Wilets IF, Nagler HM. Treatment outcome after varicocelectomy. a critical analysis. Urol Clin North Am. 1994;21(3):517-29. PMid:8059505.
25 Cozzolino DJ, Lipshultz LI. Varicocele as a progressive lesion: positive effect of varicocele repair. Hum Reprod Update. 2001;7(1):55-8.
Submitted date:
07/22/2020
Accepted date:
08/31/2020