Jornal Vascular Brasileiro
https://jvascbras.org/article/doi/10.1590/1677-5449.202301242
Jornal Vascular Brasileiro
Case Report

Left ventricle pedunculated thrombi risks and outcomes: a case report and literature review

Riscos e desfechos de trombos pedunculados no ventrículo esquerdo: relato de caso e revisão da literatura

Ahmed Ali Ali; Eman Elsayed Sakr

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Abstract

A 42-year-old male with ischemic cardiomyopathy presented with acute bilateral femoral artery embolization. After management with embolectomy and fasciotomy in both femoral arteries, transthoracic echocardiography revealed two pedunculated highly mobile left ventricle (LV) thrombi. Given the procedural risk, anticoagulation therapy was recommended over surgery. However, the bleeding risk impeded the continuation of anticoagulation, which increased the thrombus size. Multiorgan failure and disseminated intravascular coagulopathy followed and the patient died. We also systematically reviewed the PubMed and Scopus databases for pedunculated LV thrombi cases and retrieved 74 and 63 reports respectively. Of these, 37 relevant reports (45 cases) plus 11 reports from the manual search were included for data extraction, a total of 56 cases besides our case. Based on the etiologies and risks, LV thrombi are predictable and preventable, especially after ischemic events. A clear diagnostic algorithm and vigilant follow-up are needed as well as multidisciplinary management once a diagnosis is confirmed.

Keywords

left ventricle; myocardial infarction; thrombosis; emboli; risks; outcomes

Resumo

Relatamos o caso de um homem de 42 anos com cardiomiopatia isquêmica que apresentou embolização aguda bilateral das artérias femorais. Embolectomia das artérias femorais e fasciotomia foram realizadas bilateralmente e, posteriormente, o ecocardiograma transtorácico revelou a presença de dois trombos pedunculados altamente móveis no ventrículo esquerdo (VE). Diante do risco associado à abordagem cirúrgica, recomendou-se terapia anticoagulante. No entanto, o risco de sangramento impediu a continuação da anticoagulação, o que levou ao aumento dos trombos. Posteriormente, o paciente evoluiu com falência de múltiplos órgãos e coagulação intravascular disseminada, vindo a óbito. Além do relato de caso, realizamos buscas sistemáticas nas bases de dados PubMed e Scopus por casos de trombos pedunculados no VE. Foram recuperados 74 e 63 relatos, respectivamente, dos quais 37 relatos relevantes (45 casos) e 11 da busca manual foram selecionados para extração de dados, totalizando 56 casos além do nosso. Com base nas etiologias e nos riscos, os trombos no VE são previsíveis e evitáveis, especialmente após eventos isquêmicos. Isso requer um algoritmo diagnóstico claro e acompanhamento vigilante, bem como manejo multidisciplinar após confirmação do diagnóstico.

Palavras-chave

ventrículo esquerdo; infarto do miocárdio; trombose; embolia; riscos; desfechos

References

1 Lattuca B, Bouziri N, Kerneis M, et al. Antithrombotic therapy for patients with left ventricular mural thrombus. J Am Coll Cardiol. 2020;75(14):1676-85. http://doi.org/10.1016/j.jacc.2020.01.057. PMid:32273033.

2 Johansson PI, Bro-Jeppesen J, Kjaergaard J, Wanscher M, Hassager C, Ostrowski SR. Sympathoadrenal activation and endothelial damage are inter correlated and predict increased mortality in patients resuscitated after out-of-hospital cardiac arrest. a post Hoc sub-study of patients from the TTM-trial. PLoS One. 2015;10(3):e0120914. http://doi.org/10.1371/journal.pone.0120914. PMid:25789868.

3 Camaj A, Fuster V, Giustino G, et al. Left ventricular thrombus following acute myocardial infarction: JACC state-of-the-art review. J Am Coll Cardiol. 2022;79(10):1010-22. http://doi.org/10.1016/j.jacc.2022.01.011. PMid:35272796.

4 Santoro F, Stiermaier T, Tarantino N, et al. Left ventricular thrombi in Takotsubo syndrome: incidence, predictors, and management: results from the GEIST (German Italian Stress Cardiomyopathy) Registry. J Am Heart Assoc. 2017;6(12):e006990. http://doi.org/10.1161/JAHA.117.006990. PMid:29203578.

5 Templin C, Ghadri JR, Diekmann J, et al. Clinical features and outcomes of takotsubo (stress) cardiomyopathy. N Engl J Med. 2015;373(10):929-38. http://doi.org/10.1056/NEJMoa1406761. PMid:26332547.

6 Kuh JH, Seo Y. Transatrial resection of a left ventricular thrombus after acute myocarditis. Heart Vessels. 2005;20(5):230-2. http://doi.org/10.1007/s00380-004-0811-7. PMid:16160906.

7 Glikson M, Agranat O, Ziskind Z, Kaplinski E, Vered Z. From swirling to a mobile, pedunculated mass—the evolution of left ventricular thrombus despite full anticoagulation: echocardiographic demonstration. Chest. 1993;103(1):281-3. http://doi.org/10.1378/chest.103.1.281. PMid:8417899.

8 Tsukube T, Okada M, Ootaki Y, Tsuji Y, Yamashita C. Transaortic video-assisted removal of a left ventricular thrombus. Ann Thorac Surg. 1999;68(3):1063-5. http://doi.org/10.1016/S0003-4975(99)00662-1. PMid:10510010.

9 Kumar USD, Shetty SP, Sujay KR, Wali M. Left ventricular mass: a tumor or a thrombus diagnostic dilemma. Ann Card Anaesth. 2016;19(4):728-32. http://doi.org/10.4103/0971-9784.191551. PMid:27716707.

10 Grewal HK, Bansal M, Garg A, Kasliwal RR, Bhan A, Gautam D. Left ventricular thrombus and cardioembolic stroke in a patient with ulcerative colitis: a case report. Saudi J Med Med Sci. 2021;9(1):67-70. http://doi.org/10.4103/sjmms.sjmms_525_19. PMid:33519347.

11 Garg A, Hakeem H, Chennu G, et al. Left ventricular mural thrombi with multisystem thrombosis in patients with COVID-19 and myocardial injury: a case series. Eur Heart J Case Rep. 2021;5(6):ytab239. http://doi.org/10.1093/ehjcr/ytab239. PMid:34263128.

12 Cousin E, Scholfield M, Faber C, Caldeira C, Guglin M. Treatment options for patients with mobile left ventricular thrombus and ventricular dysfunction: a case series. Heart Lung Vessel. 2014;6(2):88-91. PMid:25024990.

13 Kanazawa H, Kashima I, Mochizuki Y, et al. A “bowing” pedunculated large thrombus in the left ventricle and its formation. Int J Cardiol. 2016;222:841-3. http://doi.org/10.1016/j.ijcard.2016.08.035. PMid:27522386.

14 Allende NG, Sokn F, Borracci R, et al. Giant pedunculated thrombus with normal left ventricular systolic function mimicking myxoma. Echocardiography. 2011;28(2):E31-3. http://doi.org/10.1111/j.1540-8175.2010.01262.x. PMid:21198822.

15 Lutz CJ, Bhamidipati CM, Ford B, et al. Robotic-assisted excision of a left ventricular thrombus. Innovations (Phila). 2007;2(5):251-3. http://doi.org/10.1097/imi.0b013e31815cea73. PMid:22437135.

16 Nili M, Deviri E, Jortner R, Strasberg B, Levy MJ. Surgical removal of a mobile, pedunculated left ventricular thrombus: report of 4 cases. Ann Thorac Surg. 1988;46(4):396-400. http://doi.org/10.1016/S0003-4975(10)64651-6. PMid:3178348.

17 Kharwar RB, Chandra S, Dwivedi SK, Saran RK. A pedunculated left ventricular thrombus in a women with peripartum cardiomyopathy: evaluation by three dimensional echocardiography. J Cardiovasc Ultrasound. 2014;22(3):139-43. http://doi.org/10.4250/jcu.2014.22.3.139. PMid:25309691.

18 Ito H, Bessho S, Nakamura B, Toba S, Shomura Y, Takao M. Transmitral extraction of a huge left ventricular mural thrombus using a novel mitral leaflet retractor. Clin Case Rep. 2022;10(2):e05427. http://doi.org/10.1002/ccr3.5427. PMid:35369383.

19 Singal AK, Deepti S, Sharma G, Kothari SS. Herculean mistake: mephentermine associated cardiomyopathy. Phys Sportsmed. 2021;49(1):116-22. http://doi.org/10.1080/00913847.2020.1763146. PMid:32404042.

20 Tanaka D, Unai S, Diehl JT, Hirose H. Surgical removal of a large mobile left ventricular thrombus via left atriotomy. World J Clin Cases. 2014;2(2):32-5. http://doi.org/10.12998/wjcc.v2.i2.32. PMid:24579068.

21 Jeganathan R, Ralph‐Edwards A. Left apical pedunculated thrombus with normal ventricular function mimicking an intracardiac tumor. J Card Surg. 2011;26(6):614-6. http://doi.org/10.1111/j.1540-8191.2011.01304.x. PMid:21951172.

22 Janula M, Navarro A, Bonello J, Schembri K, Borg A. Trans-aortic left ventricular thrombo-embolectomy following COVID-19 infection. J Surg Case Rep. 2021;(9):rjab426. http://doi.org/10.1093/jscr/rjab426. PMid: 34594494.

23 Marchini JFM, Rodrigues AJ, Schmidt A. A ventricular thrombus mimicking a tumour. BMJ Case Rep. 2009;2009:bcr06.2009.1944. http://doi.org/10.1136/bcr.06.2009.1944. PMid:21886661.

24 Mukai S, Fuseno H, Nakamura M, Yoshikawa J, Shomura T. Dilated cardiomyopathy complicated by a pedunculated and mobile left ventricular thrombus on ruptured false tendons. Chest. 1991;99(4):1042-3. http://doi.org/10.1378/chest.99.4.1042. PMid:2009765.

25 Park JE, Kim WJ, Choi DS, Suh SK, Whang JW, Kim HM. A large pedunculated left ventricular thrombus with recurrent systemic thromboembolism in a young man. Korean J Intern Med (Korean Assoc Intern Med). 1986;1(2):254-8. http://doi.org/10.3904/kjim.1986.1.2.254. PMid:3154622.

26 Bakhtiari RE, Khaledifar A, Kabiri M, Danesh Z. Mobile pedunculated left ventricular masses in a man with recurrent emboli. Heart Views. 2012;13(4):146-8. http://doi.org/10.4103/1995-705X.105734. PMid:23439797.

27 Chen CC, Webster GW, Morganroth J. Large mobile pedunculated left ventricular thrombus: Identification by two‐dimensional echocardiography. Clin Cardiol. 1981;4(4):189-92. http://doi.org/10.1002/clc.4960040407. PMid:7273502.

28 Rester BT, Warnock JL, Patel PB, McMullan MR, Skelton TN, Collop NA. Lysis of a left ventricular thrombus with recombinant tissue plasminogen activator. Chest. 2001;120(2):681-3. http://doi.org/10.1378/chest.120.2.681. PMid:11502681.

29 Azari A, Amini O, Lakziyan R, Sarchahi Z. Mesenteric ischemia following large left ventricular fibroid thrombosis due to myocardial infarction: a case report. Int J Surg Case Rep. 2021;81:105833. http://doi.org/10.1016/j.ijscr.2021.105833. PMid:33887862.

30 Chen Z, Robinson N, Harkness A. Pedunculated left ventricular thrombus presenting with acute ischaemic limb. Emerg Med J. 2008;25(4):216. http://doi.org/10.1136/emj.2007.049585. PMid:18356352.

31 Kumar P, Rao MS, Lalani K, Paramasivam G, Devasia T, Parikh P. Dabigatran for intracardiac thrombus, yet another promising role of a direct oral anticoagulant: a case report and short review of literature. Arch Clin Cases. 2022;9(2):75-9. http://doi.org/10.22551/2022.35.0902.10207. PMid: 35813493.

32 Eren NK, Emren SV, Duygu H, Kocabas U. Left ventricular thrombus formation in a patient with normal ejection fraction. Turk Kardiyol Dern Ars. 2013;41(7):625-8. http://doi.org/10.5543/tkda.2013.71598. PMid:24164994.

33 Daley P, Ptacin M, Horwitz M, Werner P, Almagro U, Bamrah V. Left ventricular thrombus in agnogenic myeloid metaplasia. Cardiology. 1987;74(1):53-7. http://doi.org/10.1159/000174175. PMid:3815454.

34 John RM, Sturridge MF, Swanton RH. Pedunculated left ventricular thrombus--report of two cases. Postgrad Med J. 1991;67(791):843-5. http://doi.org/10.1136/pgmj.67.791.843. PMid:1946132.

35 Lewin RF, Vidne B, Sclarovsky S, Agmon J. Two-dimensional real-time echocardiographic detection of a left ventricular aneurysm associated with mobile pedunculated thrombi. Chest. 1980;77(5):704-6. http://doi.org/10.1378/chest.77.5.704. PMid:7363697.

36 Shetty K, Sunkara N, Ahsan C. Recurrent intra-cardiac thrombosis—A unique presentation of prothrombin G20210 mutation. J Cardiol Cases. 2011;3(3):e129-32. http://doi.org/10.1016/j.jccase.2011.02.002. PMid:30524602.

37 Steve AV, Kevin RF, James GK 3rd. Left ventricular thrombus in the absence of detectable heart disease. Chest. 1989;96(2):426-7. http://doi.org/10.1378/chest.96.2.426. PMid:2752829.

38 Lew AS, Federman J, Harper RW, et al. Operative removal of mobile pedunculated left ventricular thrombus detected by 2-dimensional echocardiography. Am J Cardiol. 1983;52(8):1148-9. http://doi.org/10.1016/0002-9149(83)90554-4. PMid:6637840.

39 Chamsi-Pasha MA, Anwar AM, Nosir YF, Chamsi-Pasha H. Hanging by a thread" left ventricular thrombus in an asymptomatic soldier. Saudi Med J. 2009;30(3):436-8. PMid:19271079.

40 Early GL, Ballenger M, Hannah H 3rd, Roberts SR. Simplified method of left ventricular thrombectomy. Ann Thorac Surg. 2001;72(3):953-4. http://doi.org/10.1016/S0003-4975(00)02607-2. PMid:11565702.

41 Wohlfarter T, Hopferwieser T, Schwaighofer H, et al. An idiopathic floating left-ventricular thrombus. Dtsch Med Wochenschr. 1991;116(21):808-11. http://doi.org/10.1055/s-2008-1063682. PMid:2032531.

42 Palazzuoli V, Mondillo S, D’Aprile N, Faglia S, Palazzuoli A. Heparin treatment and resolution of left ventricular thrombosis. Int J Cardiol. 1994;43(3):338-40. http://doi.org/10.1016/0167-5273(94)90217-8. PMid:8181893.

43 Jeon GJ, Song BG, Park YH, Kang GH, Chun WJ, Oh JH. Acute stroke and limb ischemia secondary to catastrophic massive intracardiac thrombus in a 40-year-old patient with dilated cardiomyopathy. Cardiol Res. 2012;3(1):37-40. http://doi.org/10.4021/cr142w. PMid:28357023.

44 Chirillo F, Furlanetto A, Bruni A, Martines M, Stritoni P. Atypical electromechanical dissociation in a patient with recurrent pulmonary embolism. Chest. 1996;109(2):562-3. http://doi.org/10.1378/chest.109.2.562. PMid:8620738.

45 DeWitt LD, Pessin MS, Pandian NG, Paulker SG, Sonnenberg FA, Caplan LR. Benign disappearance of ventricular thrombus after embolic stroke. A case report. Stroke. 1988;19(3):393-6. http://doi.org/10.1161/01.STR.19.3.393. PMid:3354027.

46 Hwang MH, Pacold I, Loeb HS. Acute anterior myocardial infarction complicated by mural thrombus and peripheral thromboembolism despite anticoagulation. Cathet Cardiovasc Diagn. 1985;11(4):417-22. http://doi.org/10.1002/ccd.1810110411. PMid:4042158.

47 Çil H, Yavuz C, Atilgan ZA, Gunduz E, Soydinc S. Complete resolution of the left ventricular pedunculated thrombus with tirofiban infusion in a patient with severe left ventricular dysfunction. Hong Kong J Emerg Med. 2013;20(5):305-8. http://doi.org/10.1177/102490791302000508.

48 Seitz MJ, McLeod MK, O’Keefe MD, Seah PW. A rare cause of Takotsubo cardiomyopathy related left ventricular apical thrombus requiring surgery. Heart Lung Circ. 2012;21(4):245-6. http://doi.org/10.1016/j.hlc.2011.07.004. PMid:21840755.

49 Manasrah N, Abdel-Qader A, Al Sbihi A, et al. Left ventricular thrombus formation in a structurally and functionally normal heart: a case report and literature review. J Investig Med High Impact Case Rep. 2022;10:23247096221101852. http://doi.org/10.1177/23247096221101852. PMid:35619244.

50 Jeganathan R, Ralph‐Edwards A. Left apical pedunculated thrombus with normal ventricular function mimicking an intracardiac tumor. J Card Surg. 2011;26(6):614-6. http://doi.org/10.1111/j.1540-8191.2011.01304.x. PMid:21951172.

51 Erkal Z, Bayar N, Arslan Ş. A case of thrombus formation in a patient with preserved left ventricle ejection fraction and development of peripheral embolization. Cyprus J Med Sci. 2017;2(2):38-9. http://doi.org/10.5152/cjms.2017.158.

52 Maruri-Sánchez R, Diego-Nieto G, Monguió-Santín ME, Calle-Valda CM, Reyes-Copa G, Alfonso F. An intraventricular thrombus of unknown origin. Arch Cardiol Mex. 2019;89(3):267-9. PMid:31967595.

53 Müller S, Bartel T, Laube H. Left ventricular thrombus after pregnancy: choice of surgical access using dynamic three‐dimensional echocardiography. Echocardiography. 1996;13(3):293-6. http://doi.org/10.1111/j.1540-8175.1996.tb00899.x. PMid:11442934.

54 Lin CP, Tsai FC, Chu PH, et al. Acute myocardial infarction in a young man complicated with left ventricular thrombi. Jpn Heart J. 2004;45(6):1029-35. http://doi.org/10.1536/jhj.45.1029. PMid:15655278.

55 Kuroki K, Murakami T. Thoracoscopy-assisted removal of left ventricular thrombus via minithoracotomy. Asian Cardiovasc Thorac Ann. 2012;20(1):77-9. http://doi.org/10.1177/0218492311424466. PMid:22371951.

56 Rao PV, Roussak JB, Hershman MJ, Venn GE, Taylor KM. An unusual left ventricular mass. J R Soc Med. 1990;83(10):650-1. http://doi.org/10.1177/014107689008301019. PMid:2286968.

57 Zaikokuji K, Sawazaki M, Tomari S, Uemura T. Transmitral thrombectomy to treat a patient with Takotsubo cardiomyopathy. Asian Cardiovasc Thorac Ann. 2018;26(3):236-8. http://doi.org/10.1177/0218492317729618. PMid:28870088.

58 Ho JK, Dhamija N, Yezbick A, Mahajan A, Marijic J. Left ventricular mass: intraoperative transesophageal echocardiography for evaluation and management. Anesth Analg. 2008;107(4):1153-4. http://doi.org/10.1213/ane.0b013e3181806681. PMid:18806017.

59 Mukai S, Fuseno H, Nakamura M, Yoshikawa J, Shomura T. Dilated cardiomyopathy complicated by a pedunculated and mobile left ventricular thrombus on ruptured false tendons. Chest. 1991;99(4):1042-3. http://doi.org/10.1378/chest.99.4.1042. PMid:2009765.

60 Allende NG, Sokn F, Borracci R, et al. Giant pedunculated thrombus with normal left ventricular systolic function mimicking myxoma. Echocardiography. 2011;28(2):E31-3. http://doi.org/10.1111/j.1540-8175.2010.01262.x. PMid:21198822.

61 Levine GN, McEvoy JW, Fang JC, et al. Management of patients at risk for and with left ventricular thrombus: a scientific statement from the American heart association. Circulation. 2022;146(15):e205-23. http://doi.org/10.1161/CIR.0000000000001092. PMid:36106537.

62 Keren A, Goldberg S, Gottlieb S, et al. Natural history of left ventricular thrombi: their appearance and resolution in the posthospitalization period of acute myocardial infarction. J Am Coll Cardiol. 1990;15(4):790-800. http://doi.org/10.1016/0735-1097(90)90275-T. PMid:2307788.

63 Zaikokuji K, Sawazaki M, Tomari S, Uemura T. Transmitral thrombectomy to treat a patient with Takotsubo cardiomyopathy. Asian Cardiovasc Thorac Ann. 2018;26(3):236-8. http://doi.org/10.1177/0218492317729618. PMid:28870088.

64 Nili M, Deviri E, Jortner R, Strasberg B, Levy MJ. Surgical removal of a mobile, pedunculated left ventricular thrombus: report of 4 cases. Ann Thorac Surg. 1988;46(4):396-400. http://doi.org/10.1016/S0003-4975(10)64651-6. PMid:3178348.

65 Jeon GJ, Song BG, Park YH, Kang GH, Chun WJ, Oh JH. Acute stroke and limb ischemia secondary to catastrophic massive intracardiac thrombus in a 40-year-old patient with dilated cardiomyopathy. Cardiol Res. 2012;3(1):37-40. http://doi.org/10.4021/cr142w. PMid:28357023.

66 Chamsi-Pasha MA, Anwar AM, Nosir YF, Chamsi-Pasha H. Hanging by a thread" left ventricular thrombus in an asymptomatic soldier. Saudi Med J. 2009;30(3):436-8. PMid:19271079.

67 Bakhtiari RE, Khaledifar A, Kabiri M, Danesh Z. Mobile pedunculated left ventricular masses in a man with recurrent emboli. Heart Views. 2012;13(4):146-8. http://doi.org/10.4103/1995-705X.105734. PMid:23439797.

68 Marchini JFM, Rodrigues AJ, Schmidt A. A ventricular thrombus mimicking a tumour. BMJ Case Rep. 2009;2009:bcr06.2009.1944. http://doi.org/10.1136/bcr.06.2009.1944. PMid:21886661.

69 Singal AK, Deepti S, Sharma G, Kothari SS. Herculean mistake: mephentermine associated cardiomyopathy. Phys Sportsmed. 2021;49(1):116-22. http://doi.org/10.1080/00913847.2020.1763146. PMid:32404042.

70 Kharwar RB, Chandra S, Dwivedi SK, Saran RK. A pedunculated left ventricular thrombus in a women with peripartum cardiomyopathy: evaluation by three dimensional echocardiography. J Cardiovasc Ultrasound. 2014;22(3):139-43. http://doi.org/10.4250/jcu.2014.22.3.139. PMid:25309691.

71 Weinsaft JW, Kim J, Medicherla CB, et al. A novel imaging algorithm for post myocardial infarction left ventricular Thrombus–regional LV function on echocardiography as a gatekeeper for Thrombus evaluation by delayed enhancement cardiac magnetic resonance. JACC Cardiovasc Imaging. 2016;9(5):505. http://doi.org/10.1016/j.jcmg.2015.06.017. PMid:26476503.

72 Corrado PA, Macdonald JA, François CJ, Aggarwal NR, Weinsaft JW, Wieben O. Reduced regional flow in the left ventricle after anterior acute myocardial infarction: a case control study using 4D flow MRI. BMC Med Imaging. 2019;19(1):1-10. http://doi.org/10.1186/s12880-019-0404-7. PMid:31888531.

73 O’gara PT, Kushner FG, Ascheim DD, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;127(4):529-55. http://doi.org/10.1161/CIR.0b013e3182742c84. PMid:23247303.

74 Zhang Z, Si D, Zhang Q, et al. Prophylactic rivaroxaban therapy for left ventricular thrombus after anterior ST-segment elevation myocardial infarction. Cardiovascular Interventions. 2022;15(8):861-72. http://doi.org/10.1016/j.jcin.2022.01.285. PMid:35367170.

75 Shantsila E, Kozieł M, Lip GY. Anticoagulation versus placebo for heart failure in sinus rhythm. Cochrane Database Syst Rev. 2021;5(5):CD003336. http://doi.org/10.1002/14651858.CD003336.pub4. PMid:34002371.

76 Cokkinos DV, Haralabopoulos GC, Kostis JB, Toutouzas PK, HELAS investigators. Efficacy of antithrombotic therapy in chronic heart failure: the HELAS study. Eur J Heart Fail. 2006;8(4):428-32. http://doi.org/10.1016/j.ejheart.2006.02.012. PMid:16737850.

77 Weinsaft JW, Kim HW, Shah DJ, et al. Detection of left ventricular thrombus by delayed-enhancement cardiovascular magnetic resonance: prevalence and markers in patients with systolic dysfunction. J Am Coll Cardiol. 2008;52(2):148-57. http://doi.org/10.1016/j.jacc.2008.03.041. PMid:18598895.

78 Mehana EM, Shawky AM, Abdelrahman HS. Insights on the left ventricular thrombus in patients with ischemic dilated cardiomyopathy. Egypt J Radiol Nucl Med. 2021;52:246. https://doi.org/10.1186/s43055-021-00628-5.

79 Weinsaft JW, Kim J, Medicherla CB, et al. A novel imaging algorithm for post myocardial infarction left ventricular Thrombus–regional LV function on echocardiography as a gatekeeper for Thrombus evaluation by delayed enhancement cardiac magnetic resonance. JACC Cardiovasc Imaging. 2016;9(5):505. http://doi.org/10.1016/j.jcmg.2015.06.017. PMid:26476503.

80 Howick J, Chalmers I, Lind J, et al. Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence [Internet]. 2011 [cited 2023 Oct 15]. Available from: http://www.cebm.net/index.aspx?o=5653
 


Submitted date:
10/15/2023

Accepted date:
01/21/2024

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