Quais são os mecanismos celulares relacionados aos eventos tromboembólicos em pacientes com COVID-19?
What cellular mechanisms are related to thromboembolic events in patients with COVID-19?
Cristian Rodrigues do Nascimento; Júlio Martinez Santos; Sávio Breno Pires Brito; Pedro Pereira Tenório
Resumo
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Abstract
SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. This disease is beginning to be better understood in terms of its other, non-respiratory, clinical manifestations. Over the course of months caring for patients infected by the virus, clinical and laboratory changes have been identified that have prompted researchers to debate the potential that SARS-CoV-2 has to trigger an exacerbated immune response that is capable of changing endothelial homeostasis through both direct and indirect mechanisms. With the intention of contributing to this debate, a review was conducted of the possible mechanisms that could trigger these phenomena in patients with COVID-19. It is important to understand the pathophysiology of the immunological mechanisms related to this disease in order to understand the potential endothelial damage that COVID-19 can provoke.
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References
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Submitted date:
01/21/2021
Accepted date:
05/05/2021
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