Endovascular stenting with a drug-eluting stent of transplanted renal artery stenosis in a dual kidney transplanted patient
Tratamento endovascular com stent farmacológico em estenose de artéria renal transplantada de paciente com transplante renal duplo
Rajesh Vijayvergiya; Navjyot Kaur; Ganesh Kasinadhuni; Ashish Sharma; Anupam Lal; Ashwani Sood
Abstract
Keywords
Resumo
Resumo: O transplante renal continua sendo a terapia preferida para doenças renais em fase terminal. Dada a escassez de rins de doadores adequados, o doador com critérios expandidos permite que rins marginais sejam transplantados, embora haja um maior risco de falha do enxerto devido à diminuição da massa nefrótica. Para diminuir o risco de falha do enxerto, recomenda-se o transplante renal duplo (TRD), com resultados favoráveis. A estenose de artéria renal transplantada (EART) é uma das complicações vasculares mais comuns após o transplante renal. Ao contrário dos transplantes de rim simples, nos quais a EART geralmente se manifesta como sobrecarga de fluido, hipertensão descontrolada e piora das funções renais, ela pode ser clinicamente silenciosa em pacientes com TRD, pois eles têm dois rins funcionais transplantados. Relatamos aqui um caso de EART em um paciente com TRD que teve resultados clínicos favoráveis por dois anos após o sucesso do implante de stent endovascular. No entanto, ele morreu recentemente de pneumonite associada à covid-19.
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References
1 Metzger RA, Delmonico FL, Feng S, Port FK, Wynn JJ, Merion RM. Expanded criteria donors for kidney transplantation. Am J Transplant. 2003;3(Suppl. 4):114-25.
2 Moore PS, Farney AC, Sundberg AK, et al. Dual kidney transplantation: a case - control comparison with single kidney transplantation from standard and expanded criteria donors. Transplantation. 2007;83(12):1551-6.
3 Nathan HM, Conrad SL, Held PJ, et al. Organ donation in the United States. Am J Transplant. 2003;3(Suppl. 4):29-40.
4 Shafran D, Kodish E, Tzakis A. Organ shortage: the greatest challenge facing transplant medicine. World J Surg. 2014;38(7):1650-7.
5 Rao PS, Ojo A. The alphabet soup of kidney transplantation: SCD, DCD, ECD: fundamentals for the practicing nephrologist. Clin J Am Soc Nephrol. 2009;4(11):1827-31.
6 Hurst FP, Abbott KC, Neff RT, et al. Incidence, predictors and outcomes of transplant renal artery stenosis after kidney transplantation: analysis of USRDS. Am J Nephrol. 2009;30(5):459-67.
7 Hariharan S, Johnson CP, Bresnahan BA, Taranto SE, McIntosh MJ, Stablein D. Improved graft survival after renal transplantation in the United States, 1988 to 1996. N Engl J Med. 2000;342(9):605-12.
8 Fervenza FC, Lafayette RA, Alfrey EJ, Petersen J. Renal artery stenosis in kidney transplants. Am J Kidney Dis. 1998;31(1):142-8.
9 Lacombe M. Arterial stenosis complicating renal allotransplantation in man: a study of 38 cases. Ann Surg. 1975;181(3):283-8.
10 Goldblatt H, Lynch J, Hanzal RF, Summerville WW. Studies on experimental hypertension: I. The production of persistent elevation of systolic blood pressure by means of renal ischemia. J Exp Med. 1934;59(3):347-79.
11 Bruno S, Remuzzi G, Ruggenenti P. Transplant renal artery stenosis. J Am Soc Nephrol. 2004;15(1):134-41.
12 Chen W, Kayler LK, Zand MS, Muttana R, Chernyak V, DeBoccardo GO. Transplant renal artery stenosis: clinical manifestations, diagnosis and therapy. Clin Kidney J. 2015;8(1):71-8.
13 Browne RF, Tuite DJ. Imaging of the renal transplant: comparison of MRI with duplex sonography. Abdom Imaging. 2006;31(4):461-82.
14 Morais RH, Muglia VF, Mamere AE, et al. Duplex Doppler sonography of transplant renal artery stenosis. J Clin Ultrasound. 2003;31(3):135-41.
15 Granata A, Fiorini F, Andrulli S, et al. Doppler ultrasound and renal artery stenosis: an overview. J Ultrasound. 2009;12(4):133-43.
16 Greenstein SM, Verstandig A, McLean GK, et al. Percutaneous transluminal angioplasty: the procedure of choice in the hypertensive renal allograft recipient with renal artery stenosis. Transplantation. 1987;43(1):29-31.
17 Chew LL, Tan BS, Kumar K, et al. Percutaneous transluminal angioplasty of transplant renal artery stenosis. Ann Acad Med Singapore. 2014;43(1):39-43. PMid:24557464.
18 Seratnahaei A, Shah A, Bodiwala K, Mukherjee D. Management of transplant renal artery stenosis. Angiology. 2011;62(3):219-24.
19 Abate MT, Kaur J, Suh H, Darras F, Mani A, Nord EP. The use of drug-eluting stents in the management of transplant renal artery stenosis. Am J Transplant. 2011;11(10):2235-41.
20 Estrada CC, Musani M, Darras F, et al. 5 Years Experience With Drug Eluting and Bare Metal Stents as Primary Intervention in Transplant Renal Artery Stenosis. Transplant Direct. 2017;3(2):e128.