Jornal Vascular Brasileiro
https://jvascbras.org/article/doi/10.1590/S1677-54492006000300009
Jornal Vascular Brasileiro
Case Report

Utilização de células-tronco de medula óssea para tratamento de isquemia crítica de membro inferior

Use of bone marrow stem cells to treat critical ischemic limbs

José Dalmo de Araújo; José Dalmo de Araújo Filho; Emerson Ciorlin; Oswaldo Tadeu Greco; Roberto Vito Ardito; Lílian Piron Ruiz; Milton Artur Ruiz

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Resumo

Relatamos o caso de um paciente masculino de 49 anos, portador de oclusão embólica de todas as artérias da perna esquerda. Após múltiplas e fracassadas tentativas de revascularização e, também, simpatectomia lombar em outros serviços, chegou a nós com indicação de amputação no nível de perna. Propusemos o implante de células-tronco autógenas de medula óssea na panturrilha. Obteve-se um excelente resultado, com a supressão da dor em repouso, melhora da hipotermia e palidez, elevação do índice tornozelo/braço, da velocidade sistólica de pico, dos índices cintilográficos e angiográficos e sensível melhora na granulação no local da amputação do quarto e quinto pododáctilo.

Palavras-chave

Células-tronco, terapia regenerativa

Abstract

We report on the case of a 49-year-old male patient who presented with embolic occlusion of all left leg arteries. After multiple and unsuccessful revascularization attempts and lumbar sympathectomy, he was referred to us with an indication of amputation at the upper third of the leg. We suggested implanting autogenous bone marrow stem cells in his calf. Excellent immediate results were obtained with suppression of rest pain, hypothermia and paleness, elevation of ankle/brachial index, peak systolic velocities and scintigraphic and angiographic indices. There was also a considerable enhancement of healing at the amputation site of the fourth and fifth toes.

Keywords

Stem cells, regenerative therapy

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