Jornal Vascular Brasileiro
Jornal Vascular Brasileiro
Review Article

Effects of low-level laser therapy on the progress of wound healing in humans: the contribution of in vitro and in vivo experimental studies

Adeir Moreira Rocha Júnior; Beatriz Julião Vieira; Luís Carlos Ferreira de Andrade; Fernando Monteiro Aarestrup

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Low-level laser therapy is an important method for the treatment of healing processes, and several experimental studies have been carried out in search of a greater understanding of its therapeutic possibilities. The objective of this study was to review pathogenetic aspects of soft tissue repair to better understand skin lesion healing and the role of low-intensity laser in the progression of tissue healing. This study consists of a concise review of scientific literature data on the use of low-level laser and its influence on wound healing. Many studies have extensively covered the effects of using laser radiation in tissues, describing its beneficial aspects in tissue healing. However, many unanswered questions demand research on the mechanism of action and on parameters of low-level laser use in different stages of wound repair to clarify how this method acts at a cell level in healing processes.


LLLT, wound healing


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