Jornal Vascular Brasileiro
https://jvascbras.org/article/doi/10.1590/jvb.2014.020
Jornal Vascular Brasileiro
Original Article

Morbidity and mortality associated with arterial surgery site infections by resistant microorganisms

Morbimortalidade relacionada às infecções de ferida operatória ocasionadas por micro-organismos resistentes em cirurgias arteriais

Eduardo Lichtenfels; Pedro Alves D'Azevedo; Airton Delduque Frankini; Nilon Erling Jr.; Newton Roesch Aerts

http://dx.doi.org/10.1590/jvb.2014.020 J Vasc Bras, vol.13, n3, p.175-181, 2014
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Abstract

Background:Surgical site infection is a severe complication of peripheral vascular surgery with high morbidity and mortality rates.Objective:To evaluate the morbidity and mortality of infections of peripheral artery surgery sites caused by resistant microorganisms.Methods:This was a prospective study of a cohort of patients who underwent peripheral artery revascularization procedures and developed surgical site infections between March 2007 and March 2011.Results:Mean age was 63.7 years; males accounted for 64.3% of all cases. The overall prevalence of bacterial resistance to antimicrobials was 65.7%. The most common microorganism identified was Staphylococcus aureus (30%). Comparison of the demographic and surgical characteristics of both subsets (resistant versus non-resistant) detected a significant difference in length of preoperative hospital stay (9.3 days vs. 3.7 days). The subset of patients with infections by resistant microorganisms had higher rates of reoperation, lower numbers of limb amputations and lower mortality, but the differences compared to the subset without resistant infections were not significant. Long-term survival was similar.Conclusions:This study detected no statistically significant differences in morbidity or mortality between subsets with surgical wound infections caused by resistant and not-resistant microorganisms.

Keywords

surgical wound infection, drug resistance, surgery

Resumo

Contexto:A infecção de ferida operatória é uma complicação grave da cirurgia vascular periférica e está associada a elevadas taxas de morbidade e mortalidade.Objetivo:Avaliar a morbidade e a mortalidade relacionadas às infecções de ferida operatória causadas por micro-organismos resistentes em cirurgias arteriais periféricas.Métodos:Coorte prospectiva envolvendo pacientes submetidos a procedimentos de revascularização arterial periférica que desenvolveram infecção de sítio cirúrgico, entre março de 2007 e março de 2011.Resultados:A média de idade desses pacientes foi de 63,7 anos; homens representaram 64,3% de todos os casos. A prevalência total de resistência bacteriana foi de 65,7%. O micro-organismo mais isolado foi o Staphylococcus aureus (30%). Comparando-se as características demográficas e cirúrgicas das duas amostras (com e sem resistência), foi demonstrado que o tempo de permanência hospitalar apresentou diferença significativa (9,3 dias × 3,7 dias). O grupo de pacientes portadores de infecção por micro-organismo resistente apresentou elevadas taxas de reoperação, amputação de membro inferior e mortalidade, porém sem diferença estatística quando comparado ao grupo sem resistência. No longo prazo, a sobrevida foi similar.Conclusão:este estudo não demonstrou diferença estatística quanto a morbidade e mortalidade entre os grupos com infecção de ferida operatória ocasionada por micro-organismos resistentes e não resistentes.

Palavras-chave

infecção de ferida operatória, resistência medicamentosa, cirurgia

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